Synthesis of 3-((trifluoromethyl)thio)indoles via trifluoromethylthiolation of 2-alkynylazidoarenes with AgSCF3

Organofluorines have attracted growing interest in recent years. Fluorine-containing molecules have found wide applications in agrochemicals, drug development, and material technology due to unique properties of fluorine atom, i.e. strong electron-withdrawing ability and high hydrophobicity. Therefore, the introduction of fluorine atom and fluorine-containing scaffolds into organic molecules and/or heterocycles gains significant attention and is a crucial … Continue reading Synthesis of 3-((trifluoromethyl)thio)indoles via trifluoromethylthiolation of 2-alkynylazidoarenes with AgSCF3